Robaxin methocarbamol vs Flexeril cyclobenzaprine Side Effects & Uses

Both methocarbamol and cyclobenzaprine effectively relieve symptoms of acute low back pain, including pain intensity, pain-related disability and quality of life1, 2. Regarding comparative effectiveness, there is limited direct head-to-head research comparing the two medications. Studies evaluating their effectiveness have often focused on their efficacy rather than a direct comparison. The choice between Cyclobenzaprine and Methocarbamol is typically based on factors such as the individual’s medical history, tolerability, potential drug interactions, and the treatment condition.

• Usually, when patients cannot use Robaxin, other muscle relaxants are being used as an alternative.
• Zanaflex is a brand name for Tizanidine and is also a prescription medication; hence care should be taken when using this medication as the side effects are numerous.
• Robaxin can decrease the effectiveness of pyridostigmine bromide, a medication used to treat myasthenia gravis.
• Both Robaxin and Flexeril work in similar ways through acting on the central nervous system (CNS).

The recommended starting dose of Robaxin is six grams a day for the first 48 to 72 hours of treatment. Thereafter, the dosage can usually can i mix flexeril with xanax be reduced to approximately 4 grams a day. Robaxin may interact with pyridostigmine, donepezil, galantamine, rivastigmine, or tacrine.

Are Robaxin and Flexeril safe to take while pregnant or breastfeeding?

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Since Robaxin and Flexeril have CNS depressant effects, they can interact with other drugs that have similar effects. Drugs that have CNS depressant effects include barbiturates and benzodiazepines. You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling FDA-1088. Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information.

Further classified as antispasmodic agents, Robaxin and Flexeril are effective for treating acute, painful musculoskeletal conditions that cause discomfort and muscle spasms. Four popular muscle relaxants are Flexeril (cyclobenzaprine), baclofen, Robaxin (methocarbamol), and Zanaflex (tizanidine). Flexeril (a discontinued brand name in the U.S. that is still used to refer to the drug cyclobenzaprine) works at the brainstem, just below the brain, decreasing muscle activity by acting upon motor nerves. Robaxin (methocarbamol) is not fully understood, but may work on the brain and/or spinal cord. In this comparison, both drugs are under the same drug class and both have the same indications – treatment for muscle pain and spasms. Additionally, these two drugs are less sedating compared to other skeletal muscle relaxants.

What Are Methocarbamol Vs Cyclobenzaprine?

According to systematic reviews, almost all muscle relaxers are comparable in effectiveness. However, cyclobenzaprine is one of the most studied muscle relaxers with strong evidence for its effectiveness. These allergic reactions can manifest as trouble breathing, severe rash, and swelling. Seek immediate medical attention if you experience these adverse effects.

Rehab facilities along the country can help to get rid of addiction and stay clean after the treatment. In Methocarbamol vs Vicodin comparison, the former is under the drug class muscle relaxant while the latter is an opioid analgesic. In terms of Methocarbamol vs Vicodin abuse potential, Vicodin, as a narcotic analgesic combination is used for severe muscle and joint pain; however, the potential for abuse is extremely high.

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Based on individual patient response, the dose may be increased to 10 mg three times a day. Use of Flexeril for periods longer than two or three weeks is not recommended. This medication works by preventing muscle spasms without affecting overall muscle control and function. You can also order Robaxin online by visiting certified online pharmacies, but it is better to take any medications with doctor’s advice or prescription. Thus, if you are in a higher dosage range for Robaxin (i.e., 1500 mg/day or higher), then brand-name Flexeril is less expensive on a per day treatment basis. Please note that cost should not be your primary consideration in determining which of these drugs is right for you.

What are the main differences between Robaxin and Flexeril?

It’s often prescribed as part of a comprehensive treatment plan for various acute painful muscular conditions. Although all skeletal muscle relaxants should be used with caution in older patients, diazepam especially should be avoided in older patients or in patients with significant cognitive or hepatic impairment. For patients who are wondering, which is better between Methocarbamol vs Cyclobenzaprine, there is no proof yet that any particular muscle relaxant is much more effective than the other.

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